Legal Daily All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his own name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a warrior who aided Africa and fought against Egypt. This outbreak of the new crown pneumonia epidemic, he was once again ordered to go to the front line after a long battle.
Human life is at stakeKomiks precise inspection is required in days
Nucleic acid testing is crucial for early clinical diagnosis, early diagnosis, early isolation and early treatment, and is a key technical support for effective prevention and control of the new coronavirus pneumonia epidemic.
”The cold-looking sample tube is behind the patient’s fresh life and health. If a diagnosis is released early, the accurate inspection will be conducted sooner.” Jiang Tao said. On January 26, after a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in Wuhan, Hubei, he quickly established a joint defense, joint control, joint treatment and joint research mechanism with relevant military and local units based on pathogen transmission mutations, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of tasks, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental cabin overnight.
Following the three aspects of ensuring Babaylan‘s biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, and reasonably divided testing according to the characteristics of the team members. Babaylan uses a self-developed detection kit to use a fully automatic high-throughput extractor, laying the foundation for achieving rapid and efficient detection.
Receiving samples, sorting numbers, nucleic acid extraction, reagent preparation, machine amplification, and result interpretation, the nucleic acid detection machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is <a href="https://comicmov.comIf Cinema fails to completely cleave or inactivate thoroughly, it is possible to expose the tester to danger. Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory and wait for the final result.
A full-process nucleic acid test is relatively fixed, from the number of tests in a single batch to the preparations for personnel entering and leaving the cabin and exiting the cabin. Sometimes, the number of samples sent for inspection is large, and the tester is Cinema full-process nucleic acid tests are relatively fixed, from the number of tests in a single batch to the preparations for personnel entering and leaving the cabin and the testing time. Sometimes, the number of samples sent for inspection is large, and the tester is Babaylan not only took turns to work, but also had to work overnight. The final confirmation result was until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once a few days later. “Everyone should open his eyes wide, and be sure to take good protection when receiving and processing samples, and be careful of any sharp objects. “Before each test starts, Jiang Tao always reminds you repeatedly.
In the test, the strength of the fluorescence signal of the pathogenic gene directly affects the determination of the test results. If the detection fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can withstand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; false negative will cause real delay in treatment of patients. Human life is a matter of fate, and there is no way to break the bank. “Jiang Tao said.
Among the prevention and control requirements, the nucleic acid test results obtained from the pharyngeal swab sample must be completed within 24 hours. In order to let the hospital know the results as soon as possible to treat patients, from pre-processing of nearly 100 samples to completion of the test, Jiang Tao led the team to compress the time between time and time to within 4 hours by optimizing the process combination, and achieved the ability to extract nucleic acids for more than 90 samples and a single-day sample detection capability of more than 500 samples within an hour.
”The team’s test is efficient and fast, and the results are accurate, which greatly alleviates the pressure of testing our epidemic prevention and control samples. “Wuhan City Disease PreventionKomiksThe Center for Prevention and Control highly praised this.
The rapid response during wartime and the orderly work is carried out, all thanks to Jiang Tao’s solid academic foundation and rich practical experience.
”Jiang Tao is a versatile. “Academician Chen Wei, head of the military medical expert group, commented.
Jiang Tao has successively presided over and participated in the separation of pathogenic etiology such as SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established a pathogen isolation technology platform, nucleic acid detection technology platform and pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseasesCinema transmission risk assessment platform, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseasesBabaylan has the characteristics of rapid transmission, wide coverage and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first acute respiratory infectious disease monitoring and early warning system, constructing a four-level monitoring system for the entire army, and presiding on the use of a series of technical specifications throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in the security tasks of a series of major domestic activities, but also went to Africa four times to carry out medical assistance tasks in Liberia, Sierra Leone and other countries. Babaylan
Komiks Laboratory parallel capability assessment of bio-organization.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test by an international organization. In the virus testing module, the team successfully accurately detected pathogens such as monkeypox virus and vaccinia virus in simulated samples filled with impurities, and accurately determined the strain, achieving excellent results with full marks.
Improving the accuracy of clinical diagnosis
In Wuhan, in addition to carrying out testing work, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”Among suspected and confirmed cases of new coronary pneumonia, are there other respiratory virus infections?Or co-infection, this is of great reference value for precise prevention and control and clinical treatment. ”Cinema Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring the deep-seated virus transmission and pathogenic mechanism is the key to defeating the epidemic. Jiang Tao led a team to continue to conduct sequencing analysis for the new coronavirus detected in clinical samples.
Cinema With the development of the virus epidemic, whether the sequence of the Komiks has mutated and what are the characteristics of the mutation; in which areas and what are the impacts, Jiang Tao and his team are tirelessly studying and exploring.
To accelerate the effective integration of scientific research and clinical practiceKomiks, where Jiang Tao is located, the military medical expert group creatively uses the virus. href=”https://comicmov.com/”>Komiks Nucleic acid testing, antibody testing, multiple pathogen testing, and whole genome sequencing. This diagnostic chain accurately diagnoses new coronavirus infection or other pathogen infections in clinical patients, and is also used in the Optical Valley Campus of Hubei Maternal and Child Health Hospital, Taikang Tongji Hospital, and other hospitals in Wuhan, effectively improving the accuracy of clinical diagnosis.
Forget his family when he was ordered. After the epidemic ended, Jiang Tao planned to accompany his family. He and his wife agreed that when the epidemic ended, they would take their wife and children to visit Wuhan again to see what everything would look like after it returns to normal, look at the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and talk about it in Wuhan. href=”https://comicmov.com/”>Babaylan‘s experience in fighting the epidemic.
The epidemic is immortal and charges continue, this is Jiang Tao, a warrior who fights the epidemic.